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Epidermolytic palmoplantar keratoderma

1 OMIM reference -
4 associated genes
8 signs/symptoms

PROTEIN INTERACTIONS: 1

Limb-mammary syndrome

1 OMIM reference -
1 associated gene
No signs/symptoms info

Epidermolytic palmoplantar keratoderma

Limb-mammary syndrome

KRT1	(UniProt - OMIM)		TP63	(UniProt - OMIM)
KRT16	(UniProt - OMIM)
KRT6C	(UniProt - OMIM)
KRT9	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	KRT6C	(0.72)	TP63

Citations in the biomedical literature:

Epidermolytic palmoplantar keratoderma		Limb-mammary syndrome
	Synonym(s): - Diffuse erythrodermic palmoplantar keratoderma, Voerner type - Diffuse erythrodermic palmoplantar keratoderma, VÃ¶rner type - EPPK - Epidermolytic palmoplantar keratoderma of Voerner - Epidermolytic palmoplantar keratoderma of VÃ¶rner		Synonym(s): - LMS

	Classification (Orphanet): - Rare genetic disease - Rare skin disease		Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare eye disease - Rare genetic disease - Rare gynecologic or obstetric disease - Rare skin disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): (no data available)

	Epidemiological data: (no data available)		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: no data available Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: C535903

Epidermolytic palmoplantar keratoderma
	Very frequent - Autosomal dominant inheritance - Erythema / erythematous lesions / erythroderma / polymorphous erythema - Hyperkeratosis / ainhum / hyperkeratotic skin fissures - Palmoplantar hyperkeratosis / keratoderma - Warts / papillomas Frequent - Abnormal fingernails - Eczema - Hyperhidrosis / increased sweating
Limb-mammary syndrome
(no data available)